Royal Air Force Typhoon jets have operated alongside French aircraft in a joint strike against an underground arms cache in Syrian territory used by the IS group, per a report from the UK Ministry of Defence.
The site, identified by intelligence, was assessed as storing arms and explosives, the release indicated, and was located in mountains just to the north of Palmyra in Syria's central region.
"Our fighter planes utilized Paveway IV guided bombs to hit a number of access tunnels down to the depot... initial indications indicate the target was engaged successfully," the ministry announced.
There was no sign of any civilian casualties in the attack conducted Saturday night and all the aircraft returned safely, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager tanker plane.
The Islamic State group - also known as ISIS - enforced militant control over large swathes of Iraq and Syria until 2019.
"This operation underscores our UK leadership, and resolve to stand shoulder to shoulder with our partners, to eradicate any resurgence of the terrorist group and their violent and radical beliefs in the area," Britain's Defence Chief the minister stated.
RAF aircraft have carried out patrols over Syrian airspace to "prevent any attempted comeback" of the group following its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I extend gratitude to all the members of our armed forces participating in this operation for their expertise and their courage," Healey said. "They were part of numerous British troops deployed over Christmas and New Year. This mission, to take out terrorist threats who threaten our safety, highlights how British military are always on standby, all year round, keeping Britain secure at home and influential overseas."
During December, the United States armed forces executed what it described as a "large-scale strike" targeting Daesh sites in Syria, following an attack killed two American soldiers and a civilian linguist in Palmyra.
The United Nations says Islamic State still has between 5,000 and 7,000 militants in both countries.